ISSN 1662-4009 (online)

ey0018.11-13 | New insight into preconceptional and prenatal programming | ESPEYB18

11.13. Associations between exposure to gestational diabetes mellitus in utero and daily energy intake, brain responses to food cues, and adiposity in children

S Luo , BC Angelo , T Chow , JR Monterosso , PM Thompson , AH Xiang , KA Page

Diabetes Care. 2021 May;44(5):1185–1193. 10.2337/dc20-3006. https://pubmed.ncbi.nlm.nih.gov/33827804/Luo et al. performed a retrospective cohort study of 159 children (age 7–11 years), including undertaking a food cue task while in the MRI scanner, to investigate whether brain reward systems are altered by in utero exposure to ...

ey0017.2-17 | Maternal Obesity and Long-Term Infant Consequences | ESPEYB17

2.17. Children exposed to maternal obesity or gestational diabetes mellitus during early fetal development have hypothalamic alterations that predict future weight gain

KA Page , S Luo , X Wang , T Chow , J Alves , TA Buchanan , AH Xiang

To read the full abstract: Diabetes Care. 2019 Aug;42(8):1473–1480. PMID: 31332028Maternal obesity and gestational diabetes (GDM) increase the risk of offspring developing childhood obesity and type 2 diabetes. The underlying mechanisms and possible neuronal pathways are unknown but might involve changes in the hypothalamic structure and function. Novel non-invasive imaging te...